Since the first report of a new coronavirus patient in Wuhan, China, in December 2019, COVID-19 has spread rapidly around the world, causing a global pandemic. Now, researchers from CAS, a division of the American Chemical Society that specializes in scientific information solutions, have published a special report in the American Chemical Society's "ACS Central Science". In the report, they outlined the published scientific information on the potential therapeutic drugs and vaccines of the virus, and highlighted relevant patents.
Image source: ACS Cent. Sci
According to the World Health Organization, as of March 15, 2020, COVID-19 has caused more than 150,000 diagnosed illnesses and more than 5,000 deaths. This virus, called SARS-CoV-2, mainly attacks the lower respiratory tract system, causing viral pneumonia, but it may also affect the gastrointestinal system, heart, kidneys, liver, and central nervous system. If SARS-CoV-2 cannot be controlled quickly, the virus may have a devastating effect on people's lives, the global health system, and the global economy. To help researchers discover treatments and vaccines for COVID-19, Cynthia Liu led a team of CAS scientists to analyze published scientific data on SARS-CoV-2 and related coronaviruses.
The researchers reviewed a large number of journal articles related to COVID-19 and SARS-CoV-2, as well as patents related to human coronavirus. From the last week of 2019 to March 1, 2020, more than 500 virus-related journal articles were published in electronic or printed form, and the number is steadily increasing every week. Topics include clinical manifestations, treatment options, viral structure and mechanism, antiviral drugs, and diagnosis. To date, there have been more than 500 patents for vaccines and therapeutic drugs (such as antibodies, cytokines, and nucleic acids) that can help prevent or treat coronavirus infections. Because SARS-CoV-2 is similar to other coronaviruses, such as SARS-CoV-1 and MERS-CoV, the researchers emphasized previous treatments for these other viruses, and these methods are also applicable to SARS-CoV-2.