Polyinosinic–polycytidylic Acid Sodium Salt CAS 24939-03-5/ 42424-50-0

Polyinosinic–polycytidylic Acid Sodium Salt CAS 24939-03-5/ 42424-50-0

CAS NO: 24939-03-5 / 42424-50-0
Molecular Formula: C19H27N7O16P2
Molecular Weight: 671.40
MDL NO: MFCD24369576 /MFCD00131984
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Product Details

Product Description:

Product Name: Polyinosinic–polycytidylic acid sodium salt (Poly IC) (PIC) CAS NO:24939-03-5/ 42424-50-0






Chemical & Physical Properties:

Appearance: white to off-white powder

Assay : ≥50.0%

Boiling point:851.4℃ at 760mmHg



Polyinosinic:polycytidylic acid (usually abbreviated poly I:C) is an immunostimulant. It is used in the form of its sodium salt to simulate viral infections.

Poly I:C is known to interact with toll-like receptor 3 (TLR3), which is expressed in the membrane of B-cells, macrophages and dendritic cells. Poly I:C is structurally similar to double-stranded RNA, which is present in some viruses and is a "natural" stimulant of TLR3. Thus, Poly I:C can be considered a synthetic analog of double-stranded RNA and is a common tool for scientific research on the immune system.


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