Product Name: Polyinosinic–polycytidylic acid sodium salt (Poly IC) (PIC) CAS NO:24939-03-5/ 42424-50-0
Chemical & Physical Properties:
Appearance: white to off-white powder
Assay : ≥50.0%
Boiling point:851.4℃ at 760mmHg
Polyinosinic:polycytidylic acid (usually abbreviated poly I:C) is an immunostimulant. It is used in the form of its sodium salt to simulate viral infections.
Poly I:C is known to interact with toll-like receptor 3 (TLR3), which is expressed in the membrane of B-cells, macrophages and dendritic cells. Poly I:C is structurally similar to double-stranded RNA, which is present in some viruses and is a "natural" stimulant of TLR3. Thus, Poly I:C can be considered a synthetic analog of double-stranded RNA and is a common tool for scientific research on the immune system.
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