2-Chloroadenosine CAS 146-77-0

2-Chloroadenosine CAS 146-77-0

CAS NO: 146-77-0
Molecular Formula: C10H12ClN5O4
Molecular Weight: 301.686
EINECS NO: 205-678-3
MDL NO: MFCD00005734
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Product Details

Product Description:

Product Name: 2-Chloroadenosine CAS NO:146-77-0

 

Synonyms:

6-Amino-2-chloropurine riboside;

2-CADO Hydrate;

 

Chemical & Physical Properties:

Appearance: White powder

Assay : ≥99.0%

Density: 2.19g/cm3

Boiling Point:643.3℃ at 760mmHg

Melting Point:162℃

Flash Point: 342.8℃

 

 

2-Chloroadenine nucleoside is a pharmaceutical intermediate, which can be used to prepare 2-(3,3,3-trifluoropropylthio)adenosine, which can be used as a P2Y12 antagonist An important intermediate of the anti-platelet aggregation drug Cangrelor, which belongs to the synthetic field of medicinal chemistry.

2-Chloroadenosine, a stable adenosine analogue,  Since 2-chloroadenosine is not deaminated by adenosine deaminase and is less rapidly taken up by the brain than adenosine, 2-chloroadenosine led to more marked increase in CBF than adenosine. 2-Chloroadenosine is a transported permeant for the nucleoside transporter in human erythrocytes.

 

 

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