Tenofovir Disoproxil Fumarate CAS 202138-50-9

Tenofovir Disoproxil Fumarate CAS 202138-50-9

CAS NO: 202138-50-9
Molecular Formula: C23H34N5O14P
Molecular Weight: 635.515
EINECS NO: 687-766-5
MDL NO: MFCD08141829
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Product Details

Product Description:

Product Name: Tenofovir Disoproxil Fumarate CAS NO:202138-50-9

 

Synonyms:

9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine fumarate;

 

Chemical & Physical Properties:

Appearance : white to beige powder

Assay :≥99.0%

Density:1.45 g/cm3

Boiling Point:642.7℃ at 760 mmHg

Flash Point:342.5℃

Melting Point:219℃

 

Tenofovir fumarate is a nucleotide antiviral drug developed and marketed by Gilead in the United States. It was approved by the FDA in 2001 for the treatment of human immunodeficiency virus (HIV) infection. It was launched in the European Union in 2002 and approved for the treatment of HIV-1 and chronic hepatitis B. Tenofovir disoproxil fumarate, as a nucleotide reverse transcriptase inhibitor, is an orally-opened ring-opening nucleotide phosphate prodrug. After oral absorption, it quickly transforms into tenofovir and exerts its efficacy. Due to its high bioavailability, precise curative effect and good tolerance, TDF has now become the recommended first-line anti-HIV drug with the highest sales.

 

 

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