Sitagliptin CAS 486460-32-6

Sitagliptin CAS 486460-32-6

CAS NO: 486460-32-6
Molecular Formula: C16H15F6N5O
Molecular Weight: 407.314
EINECS NO: 690-730-1
MDL NO: MFCD09838015
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Product Details

Product Description:

Product Name: Sitagliptin CAS NO:486460-32-6


Synonyms:

(3R)-3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;


Chemical & Physical Properties:

Appearance : White to off-white power

Assay :≥99.0%

Density:1.614g/cm3

Boiling Point:529.905℃ at 760 mmHg

Flash Point:274.277℃


Sitagliptin is the first dipeptidyl peptidase-4 (DPP-4) inhibitor approved for the treatment of type 2 diabetes, which can prevent and treat type 2 diabetes, hyperglycemia, insulin resistance, obesity and hypertension And certain complications. Sitagliptin phosphate was developed by Merck and was launched in Mexico and the United States in 2006. It was approved by the European Union in 2007 for the treatment of type 2 diabetes. At present, sitagliptin phosphate tablets have become the second largest oral diabetes drug in the United States.



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