(S)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one CAS 189028-95-3

(S)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one CAS 189028-95-3

CAS NO: 189028-95-3
Molecular Formula: C20H20FNO4
Molecular Weight: 357.376
EINECS NO: 606-165-0
MDL NO: MFCD13194798
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Product Details

Product Description:

Product Name:(S)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one CAS NO:189028-95-3

 

Synonyms:

3-[5-(p-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-2-oxazolidinone;

3-[(5S)-(4-fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one;

(4S)-4-phenyl-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one;

 

Chemical & Physical Properties:

Appearance : White to Off-White powder

Assay :≥99.0%

Density:1.297g/cm3

Boiling Point:572.73℃ at 760 mmHg

Flash Point:300.17℃

 

 

(S)-3-((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one is used to Ezetimibe Intermediate.

Ezetimibe's current clinical drugs for the treatment of hyperlipidemia mainly include cholesterol synthesis inhibitors, phenoxy acids and bile acid sequestrants. Ezetimibe acts on the brush border of small intestinal cells to selectively inhibit the absorption of cholesterol in the biliary tract and food without affecting the absorption of fat-soluble vitamins, triglycerides and bile acid.



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