CAS NO: 143900-44-1
Molecular Formula: C10H19NO3
Molecular Weight: 201.26
EINECS NO: 626-373-5
MDL NO: MFCD04115307 / MFCD06659041
CAS NO: 143900-44-1
Molecular Formula: C10H19NO3
Molecular Weight: 201.26
EINECS NO: 626-373-5
MDL NO: MFCD04115307 / MFCD06659041
Product Description:
Product Name: (S)-1-Boc-3-hydroxypiperidine CAS NO:143900-44-1
Synonyms:
(S)-1-Tert-Butoxycarbonyl-3-Hydroxypiperidine;
(S)-3-Hydroxy-Piperidine-1-Carboxylicacidtert-Butylester;
(S)-3-Hydroxy-1-(Tert-Butoxycarbonyl)Piperidine;
(S)-1-Boc-3-Piperidinol;
(S)-N-(Tert-Butoxycarbonyl)-3-Hydroxypiperidinehydrochloride;
(S)-N-Boc-3-Hydroxypiperidine;
(S)-Tertbutyl-3-Hydroxypiperidine-1-Carboxylate;
(S)-1-(tert-Butoxycarbonyl)-3-hydroxypiperidine;
Chemical & Physical Properties:
Appearance : White to Pale Yellow powder.
Assay : ≥99.0%
Density: 1.107g/cm3
Melting point: 34-40℃
Boiling Point: 292.3℃ at 760 mmHg
Flash Point: 110℃
Refractive Index: 1.495
Vapor Pressure: 0.0mmHg at 25°C
PSA: 49.77000
LogP: 1.31610
Pka: 14.74±0.30(Predicted)
Solubility: Soluble in methanol.
Category: Piperidines;Piperazine; Pharmaceutical/API Drug Intermediates;
Safety Information:
HS Code: 2933399090
Safety Statements: S26
Risk Statements:R36/37/38
Hazard Codes: Xi
Storage：Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Application:
1,1-dimethylethyl (3S)-3-hydroxypiperidine-1-carboxylate is an important chiral intermediate for the synthesis of ibrutinib, an anticancer drug targeting B-cell malignancies. Synthesis of pharmaceutical intermediates including ibrutinib, the API of the newly approved drug Imbruvica, for the treatment of lymphoma.
Our factory manufacture’s (3S)-1-(tert-Butyloxycarbonyl)piperidine-3-ol , mature technology, stable output, quality assurance.
Inventory Status : In Stock.
We can provide (S)-3-hydroxy-N-Boc-piperidine COA (certificate of analysis), (S)-1-BOC-Piperidin-3-ol MOA (Method of Analysis), (3S)-1-(tert-Butoxycarbonyl)-3-hydroxypiperidine ROS (Route of synthesis), (S)-N-tert-Butoxycarbonyl-3-hydroxypiperidine MSDS (Material Safety Data Sheet) and other support for you !
we can supply Ibrutinib And Intermediates:
Ibrutinib And Intermediates | CAS NO |
Ibrutinib | |
1-Piperidinecarboxylicacid,3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-,1,1-dimethylethylester,(3R)- | |
(S)-1-Boc-3-hydroxypiperidine | |
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine | |
5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine | |
5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile | |
(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-aminedihydrochloride | |
4-Amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine | |
4-Phenoxyphenyl boronic acid |
If you are interested in our products or have any questions, please feel free to contact us!
Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.
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