(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol CAS 127852-28-2

Product Description:

Product Name: (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol CAS NO:127852-28-2

Synonyms:

(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethan-1-ol;

Chemical & Physical Properties:

Appearance: white to off-white powder

Assay :≥99.0%

Density:1.376 g/cm3

Boiling Point:175.8℃ at 760 mmHg

Flash Point:60.1℃

Melting Point:53-58℃

(R)-3,5-Bis(trifluoromethyl)-α-methylbenzyl Alcohol is an important chiral intermediate for the synthesis of antiemetic drug Aprepitant. Aprepitant was used in the 2003 American food and Drug Administration (FDA) approved drugs to reduce vomiting and delayed vomiting. At the same time, the alcohol is also an important chiral intermediate for NK1 receptor antagonists and synthetic antidepressants.

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