Macitentan CAS NO: 441798-33-0

Macitentan CAS NO: 441798-33-0

CAS NO: 441798-33-0
Molecular Formula: C19H22Br2N6O4S
Molecular Weight: 590.28
EINECS NO: 1308068-626-2
MDL NO: MFCD17167076
Chat Now

Product Details

Product Description

Product Name: Macitentan CAS NO: 441798-33-0





N-[5-(4-Bromophenyl)-6-{2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy}-4-pyrimidinyl]-N'-propylsulfuric diamide;







Chemical & Physical Properties

Appearance : White powder

Assay :≥99.0%


Boiling point:692.4°Cat 760 mmHg

Flash Point:372.5℃



Macitentan (trade name Opsumit) is an endothelin receptor antagonist (ERA) approved for the treatment of pulmonary arterial hypertension (PAH). The other two ERAs marketed as of 2014 are bosentan and ambrisentan. Macitentan is a dual ERA, meaning that it acts as an antagonist of two endothelin (ET) receptor subtypes, ETA and ETB. However, macitentan has a 50-fold increased selectivity for the ETA subtype compared to the ETB subtype. The drug received approval from the U.S. Food and Drug Administration (FDA) on October 13, 2013.



If you are interested in our products or have any questions, please feel free to contact us!




Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.


Hot Tags: macitentan cas no: 441798-33-0, manufacturers, suppliers, factory, buy, in stock, 3-Chloropyrazine-2-carbonitrile, CAS 262368-30-9, Saxagliptin, Olaparib, CAS 553-67-5, 6-bromo-3-hydroxypyrazine-2-carboxamide


You Might Also Like