HBTU CAS 94790-37-1

HBTU CAS 94790-37-1

CAS NO: 94790-37-1
Molecular Formula: C11H16F6N5OP
Molecular Weight: 379.242
EINECS NO: 619-076-7
MDL NO: MFCD00075445
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Product Details


Product Description:

Product Name: HBTU CAS NO: 94790-37-1



O-(Benzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium Hexafluorophosphate;



Chemical & Physical Properties:

Appearance: white crystalline powder

Assay :≥99.0%

Flash Point:200℃

Melting point:200℃

Water Solubility:acetonitrile: 0.1 g/mL, clear


HBTU (2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate) is a coupling reagent used in solid phase peptide synthesis. It was introduced in 1978 and shows resistance against racemization. It is used because of its mild activating properties.


HBTU is a coupling agent for peptide synthesis. The main advantages are: very low racemization, simple reaction conditions, short reaction time, and high yield; the latest research shows that the crystal and solution structure of the coupling agent is guanidine salt N -Oxides, not urea cationic compounds.


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