Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate CAS 5909-24-0

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate CAS 5909-24-0

CAS NO: 5909-24-0
Molecular Formula: C8H9ClN2O2S
Molecular Weight: 232.687
EINECS NO: 227-619-0
MDL NO: MFCD00006085
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Product Details

Product Description:

Product Name: Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate CAS NO:5909-24-0





5-Pyrimidinecarboxylic acid, 4-chloro-2-(methylthio)-, ethyl ester;


Chemical & Physical Properties:

Appearance : White to light yellow powder

Assay :≥99.0%

Density: 1.37g/cm3

Melting Point:60-63℃

Boiling Point:335.7℃at 760 mmHg

Flash Point:156.8℃



4-Chloro-2-methylthiopyrimidine-5-carboxylic acid ethyl ester is an organic synthesis intermediate and pharmaceutical intermediate, mainly used in the synthesis of an important intermediate of avanafil. Avanafil is an oral fast-acting, highly selective phosphodiesterase-5 (PDE-5) inhibitor, used to treat male erectile dysfunction. Application of ethyl 4-chloro-2-methylsulfanylpyrimidine-5-carboxylate as organic synthesis intermediates and pharmaceutical intermediates, used in laboratory research and development process and chemical medicine synthesis process.



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