Product Name: Epirubicin Hydrochloride CAS NO: 56390-09-1
5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-.α.-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride;
Chemical & Physical Properties:
Appearance: Orange-Red Crystalline Solid
Boiling Point:810.3℃ at 760 mmHg
Epirubicin hydrochloride is the main isomer of doxorubicin, which is the trans configuration of the C4 hydroxyl group in the amino sugar moiety of doxorubicin. Its main mechanism is to insert directly between adjacent base pairs of DNA, form a reversible combination with DNA double helix, interfere with the transcription process, thereby inhibit the synthesis of DNA and RNA, and achieve the purpose of treating tumors. In addition, epirubicin hydrochloride has an inhibitory effect on topoisomerase Ⅱ, can also act on the nucleus, and can also affect the cell membrane and its operation system of tumor cells. It is a cell cycle non-specific drug and is effective for a variety of transplanted tumors.
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