Dorzagliatin CAS 1191995-00-2

Dorzagliatin CAS 1191995-00-2

CAS NO: 1191995-00-2
Molecular Formula: C22H27ClN4O5
Molecular Weight: 462.927
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Product Details

Product Description

Product Name: dorzagliatin CAS NO:1191995-00-2




(S)-2-[4-(2-chloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid [1-((R)-2,3-dihydroxy-propyl)-1H-pyrazol-3-yl]-amide;



Chemical & Physical Properties

Appearance : Solid

Assay : ≥98.0%


Boiling Point: 761.7°C at 760 mmHg

Flash Point:414.5℃



Dorzagliatin, also known as HMS 5552, RO5305552 and sinogliatin, is a novel Dual-Acting Glucokinase Activator, which Improves Glycaemic Control and Pancreatic β-Cell Function in Patients With Type 2 Diabetes. By addressing the defect of the glucose sensor function of glucokinase, dorzagliatin has the potential to restore the impaired glucose homeostasis state of people with type 2 diabetes and serve as a first-line standard-of-care therapy for the treatment of the disease, or as a cornerstone therapy when taken in combination with currently approved anti-diabetes drugs.



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