Product Name: Diethyl ethoxymethylenemalonate CAS NO: 87-13-8
Propanedioic acid, (ethoxymethylene)-, diethyl ester;
Chemical & Physical Properties:
Appearance: Clear colorless to light yellow liquid
Boiling Point:279-281℃ at 760 mmHg
Water Solubility: insoluble
Uses: Propanedioic acid, 2-(ethoxymethylene)-, diethyl ester is an important organic raw material with a variety of active groups in the molecule, which can undergo condensation polymerization and cyclization condensation with a variety of substances. It is also an important drug intermediate It is widely used in the synthesis of medicines, pesticides and additives, and is an intermediate for the production of chloroquine; norfloxacin; romefloxacin.
Synthesis method: The synthesis of Diethyl ethoxymethylenemalonate usually adopts the condensation reaction of diethyl malonate and triethyl orthoformate and removes a part of ethanol to obtain a condensation intermediate. The condensation intermediate eliminates one molecule of ethanol to obtain the product.
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