Dacomitinib CAS 1110813-31-4

Product Description

Product Name: Dacomitinib CAS NO:1110813-31-4

Synonyms:

Dacomitinib [USAN];

Dacomitinib (USAN/INN);

(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide;

(2e)-N-{4-[(3-Chloro-4-Fluorophenyl)amino]-7-Methoxyquinazolin-6-Yl}-4-(Piperidin-1-Yl)but-2-Enamide;

(E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide;

Chemical & Physical Properties

Appearance : White to Pale Yellow Solid.

Assay : ≥99.0%

Melting Point:184-187°C

Dacomitinib is an Erb-inhibitor, or an inhibitor of the members of the epidermal growth factor receptor family. Used as an ant-cancer agent due to observation of over-expressed epidermal growth factor receptor in nearly all cases of squamous cell carcinoma in the head and neck.

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