Crizotinib CAS 877399-52-5

Crizotinib CAS 877399-52-5

CAS NO: 877399-52-5
Molecular Formula: C21H22Cl2FN5O
Molecular Weight: 450.337
EINECS NO: 638-814-9
MDL NO: MFCD12407409
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Product Details

Product Description:

Product Name: Crizotinib CAS NO: 877399-52-5



Synonyms:

3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;


Chemical & Physical Properties:

Appearance :white to light yellow powder

Assay :≥99.0%

Density:1.475g/cm3

Boiling Point:599.2℃ at 760 mmHg

Flash Point:316.2℃



Crizotinib is a targeted therapy drug for non-small cell lung cancer developed by Pfizer in the United States. Its trade name is Xalkori. Xalkori is a cutting-edge and epoch-making drug in the field of lung cancer targeted therapy. It was approved in the United States in August 2011. It was launched on the market and was written into the international lung cancer treatment guidelines at the end of the year as the first-line medication for ALK-positive patients. It is mainly used in the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) patients who are positive for anaplastic lymphoma kinase (ALK) determined by the SFDA-approved test method.



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