Cinacalcet Hydrochloride CAS 364782-34-3

Product Description:

Product Name: Cinacalcet Hydrochloride CAS NO:364782-34-3

Synonyms:

Cinacalcet HCl;

N-[(1R)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine,hydrochloride;

(R)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride;

Chemical & Physical Properties:

Appearance: Off-White to Tan powder

Assay :≥98.0%

Boiling Point:440.9℃ at 760 mmHg

Flash Point:220.5℃

Melting point:175-177℃

Cinacalcet is a calcimimetic, which can improve the disorder of bone metabolism in uremia, and can delay the progression of calcification of blood vessels and valves in dialysis patients. However, long-term use of cinacalcet can also cause side effects such as nausea and vomiting, hypocalcemia, and excessive suppression of parathyroid hormone (PTH). Cinacalcet is characterized by not only reducing the level of PTH in the whole serum, but also reducing the level of serum calcium, serum phosphorus and serum calcium phosphorus product. It can inhibit the occurrence and progression of cardiovascular diseases caused by ectopic calcification.

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