Product Name: Avosentan CAS NO:290815-26-8
Synonyms:
N-[6-methoxy-5-(2-methoxyphenoxy)-2-pyridin-4-ylpyrimidin-4-yl]-5-methylpyridine-2-sulfonamide;
2-Pyridinesulfonamide,N-[6-methoxy-5-(2-methoxyphenoxy)-2-(4-pyridinyl)-4-pyrimidinyl]-5-methyl-;
Chemical & Physical Properties
Appearance : Off-white to white solid
Assay :≥98.0%
Density:1.364 g/cm3
Boiling Point:575.5℃ at 760 mmHg
Flash Point:301.8℃
Avosentan is a competitive antagonist of Endothelin-1 (ET-1) with a high selectivity for the ETA receptor. Avosentan may be a potential option in the treatment of glaucoma.
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