Avanafil CAS 330784-47-9

Avanafil CAS 330784-47-9

CAS NO: 330784-47-9
Molecular Formula: C23H26ClN7O3
Molecular Weight: 483.951
EINECS NO: 841-424-3
MDL NO: MFCD11977961
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Product Details

Product Description:

Product Name: Avanafil CAS NO: 330784-47-9

 

Synonyms:

4-[[(3-Chloro-4-Methoxyphenyl)Methyl]Amino]-2-[(2S)-2-(Hydroxymethyl)-1-Pyrrolidinyl]-N-(2-Pyrimidinylmethyl)-5-Pyrimidinecarboxamide;

 

Chemical & Physical Properties:

Appearance :White powder

Assay :≥98.0%

Density: 1.372g/cm3

Melting Point:150-152℃

 

 

Avanafil is a PDE5 inhibitor approved for erectile dysfunction by the FDA on April 27, 2012 and by EMA on June 21, 2013. Avanafil is known by the trademark names Stendra and Spedra and was developed by Vivus Inc. In July 2013 Vivus announced partnership with Menarini Group, which will commercialise and promote Spedra in over 40 European countries plus Australia and New Zealand. Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina. Other similar drugs are sildenafil, tadalafil and vardenafil. The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 30–45 minutes.

 

 

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.

 

 


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