Aripiprazole CAS 129722-12-9

Aripiprazole CAS 129722-12-9

CAS NO: 129722-12-9
Molecular Formula: C23H27Cl2N3O2
Molecular Weight: 448.385
EINECS NO: 603-355-5
MDL NO: MFCD00892072
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Product Details

Product Description:

Product Name: Aripiprazole CAS NO:129722-12-9

 

 

Synonyms:

7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone;

7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one;

 

 

Chemical & Physical Properties:

Appearance :White to Off-white powder

Assay :≥99.0%

Density:1.263 g/cm3

Boiling Point:646.2℃ at 760 mmHg

Melting Point:139℃

Flash Point:344.6℃

 

 

Aripiprazole is a new type of highly fat-soluble quinolinone derivative. Its pharmacological action is characterized as a post-synaptic dopamine D2 receptor antagonist and a presynaptic dopamine D2 receptor agonist. It also has the effect of stimulating D1, D3, and D4 receptors; it has a dual effect of partial receptor antagonism or activation on 5-HT1A receptor; it has a complete antagonistic effect on 5-H Chemicalbook T2A receptor. This feature is different from the first-generation and atypical antipsychotic drugs, that is, the second-generation antipsychotic drugs, so it is called the dopamine system stabilizer or the third-generation antipsychotic drugs. Since the last century, it has been mainly used clinically for the treatment of schizophrenia, schizophrenic emotional psychosis and other psychotic disorders.

 

 

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