Afatinib Dimaleate CAS 850140-73-7

Afatinib Dimaleate CAS 850140-73-7

CAS NO: 850140-73-7
Molecular Formula: C32H33ClFN5O11
Molecular Weight: 718.083
EINECS NO: 810-416-1
MDL NO: N/A
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Product Details

Product Description

Product Name: Afatinib Dimaleate CAS 850140-73-7

 

 

Synonyms:

Afatinib maleate (JAN);

Gilotrif (TN);

Afatinib dimaleate (USAN);

(Z)-but-2-enedioic acid,(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide;

Afatinib maleate;;

 

 

Chemical & Physical Properties

Appearance :Off-white solid.

Assay : ≥99.5%

 

Afatinib, a bismaleate, is an intermediate of organic synthesis and medicine, which can be used in the process of laboratory research and development and chemical medicine synthesis.

Afatinib, a new generation of oral small molecule tyrosine kinase inhibitor (TKI), is an irreversible erbbchemicalbook family blocker, which can act on the whole ErbB family including EGFR. Different from the first generation of reversible egfrtki, afartinib will irreversibly combine with EGFR, so as to close the signal pathway of cancer cells and inhibit tumor growth.

 

 

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