Afatinib CAS 439081-18-2

Afatinib CAS 439081-18-2

CAS NO:439081-18-2
Molecular Formula:C24H25ClFN5O3
Molecular Weight:485.94
EINECS NO:1308068-626-2
MDL NO:MFCD12407405
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Product Details

Product Description

Product Name: Afatinib CAS NO:439081-18-2

 

 

Synonyms:

Tovok;BIBW2992;

(S)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide;

2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-;

(E/Z)-Afatinib;

Afatinib cis-trans isomer;

2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-;

(S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide;

(2E)-N-(4-[(3-chloro-4-fluorophenyl)amino]-7-{[(3S)-tetrahydrofuran-3-yl]oxy}quinazolin-6-yl)-4-(dimethylamino)but-2-enamide;

 

 

Chemical & Physical Properties

Appearance :Off-white solid.

Assay : ≥99.5%

 

Density

1.380g/cm3

Boiling Point

676.917ºC at 760 mmHg

Melting Point

100 - 102 °C

Flash Point

363.186ºC

Refractive Index

1.668

 

BIBW 2992 is an anilino-quinazoline that irreversibly inhibits EGFR and HER2 kinase activity.

 

 

If you are interested in our products or have any questions, please feel free to contact us!

 

 

Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.


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