4-phenylbutyric Acid CAS 1821-12-1

4-phenylbutyric Acid CAS 1821-12-1

CAS NO: 1821-12-1
Molecular Formula: C10H12O2
Molecular Weight: 164.201
EINECS NO: 217-341-8
MDL NO: MFCD00004403
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Product Details


Product Description:

Product Name: 4-phenylbutyric acid CAS NO:1821-12-1

 

Synonyms:

Phenylbutyric-4 acid;

 

Chemical & Physical Properties:

Appearance: white to slightly yellowish crystalline powder

Assay :≥99.0%

Density:1.1g/cm3

Boiling Point:290.7℃ at 760 mmHg

Melting point:49-52℃

Flash point:187.9℃

Water Solubility :5.3 g/L at 40℃

 

4-Phenylbutyric acid is a monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apopto is in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.

 

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