Product Name: 4-Nitrobenzyl (2S,4S)-4-acetylthio-2-[[N-sulfamoyl-N-(tert-butoxycarbonyl)amino]methyl]pyrrolidine-1-carboxylate CAS NO:491878-06-9
Chemical & Physical Properties:
Appearance: off-white to light yellow powder
Boiling Point:686.8℃ at 760 mmHg
(4-nitrophenyl)methyl (2S,4S)-4-acetylsulfanyl-2-[[(2-methylpropan-2-yl)oxycarbonyl-sulfamoylamino]methyl]pyrrolidine-1-carboxylate is used to synthesize the penem antibiotic Doripemen.
Doripenem is a new type of carbapenem antibiotic developed by Shionoyoshi Company of Japan. It has a broad antibacterial spectrum and is stable to most β-lactamases, including penicillinase, cephalosporinase and extended-spectrum β-lactamase. Amidases (ESBLs).
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