4-Nitrobenzyl (2S,4S)-4-acetylthio-2-[[N-sulfamoyl-N-(tert-butoxycarbonyl)amino]methyl]pyrrolidine-1-carboxylate CAS 491878-06-9

4-Nitrobenzyl (2S,4S)-4-acetylthio-2-[[N-sulfamoyl-N-(tert-butoxycarbonyl)amino]methyl]pyrrolidine-1-carboxylate CAS 491878-06-9

CAS NO: 491878-06-9
Molecular Formula: C20H28N4O9S2
Molecular Weight: 532.588
EINECS NO: 610-446-3
MDL NO: MFCD14635210
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Product Details


Product Description:

Product Name: 4-Nitrobenzyl (2S,4S)-4-acetylthio-2-[[N-sulfamoyl-N-(tert-butoxycarbonyl)amino]methyl]pyrrolidine-1-carboxylate CAS NO:491878-06-9





Chemical & Physical Properties:

Appearance: off-white to light yellow powder

Assay :98.0%

Density:1.45 g/cm3

Boiling Point:686.8 at 760 mmHg

Melting Point:124-132

Flash Point:369.2



(4-nitrophenyl)methyl (2S,4S)-4-acetylsulfanyl-2-[[(2-methylpropan-2-yl)oxycarbonyl-sulfamoylamino]methyl]pyrrolidine-1-carboxylate is used to synthesize the penem antibiotic Doripemen.

Doripenem is a new type of carbapenem antibiotic developed by Shionoyoshi Company of Japan. It has a broad antibacterial spectrum and is stable to most β-lactamases, including penicillinase, cephalosporinase and extended-spectrum β-lactamase. Amidases (ESBLs).


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