4-Iodo-3-nitrobenzamide CAS 160003-66-7

4-Iodo-3-nitrobenzamide CAS 160003-66-7

CAS NO: 160003-66-7
Molecular Formula: C7H5IN2O3
Molecular Weight: 292.03
EINECS NO: 685-396-9
MDL NO: MFCD11110639
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Product Details

Product Description:

Product Name: 4-Iodo-3-nitrobenzamide CAS NO: 160003-66-7

 

 

Synonyms:

Iniparib (BSI-201);

4-Iodo-3-nitrobenzamide;

Benzamide, 4-iodo-3-nitro-;

 

 

Chemical & Physical Properties:

Appearance : yellow solid

Assay :≥99.0%

Density:2.056g/cm3

Boiling Point:344.75℃ at 760 mmHg

Flash Point:162.3℃

 

 

Iniparib (previously BSI 201) (4-iodo-3-nitrobenzamide) was a drug candidate for cancer treatment. It was originally believed to act as an irreversible inhibitor of PARP1 (hence, a PARP inhibitor) and possibly other enzymes through covalent modification, but its effects against PARP were later disproven. It underwent clinical trials for treatment of some types of breast cancer, but was discontinued after disappointing Phase III clinical trials.

 

 

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