4-hydroxyindole CAS 2380-94-1

4-hydroxyindole CAS 2380-94-1

CAS NO: 2380-94-1
Molecular Formula: C8H7NO
Molecular Weight: 133.147
EINECS NO: 219-177-2
MDL NO: MFCD00005667
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Product Details

Product Description:

Product Name: 4-hydroxyindole CAS NO:2380-94-1

 

Synonyms:

4-hydroxy-indole;

1H-Indol-4-ol;

4-hydroxy-1H-indole;

 

Chemical & Physical Properties:

Appearance: off-white powder

Assay :≥99.0%

Density:1.327g/cm3

Boiling Point:343.2℃ at 760 mmHg

Flash Point: 161.4℃

Melting point: 97-102℃

 

Used as pharmaceutical intermediates.

Production method: Using resorcinol as raw material, isomerization, catalytic hydrogenation, and then cyclization with ethyl bromopyruvate to prepare 4-oxotetrahydrogumarone carboxylic acid. It is added to a methanol solution saturated with ammonia and heated in an autoclave to generate 4-oxotetrahydroindole. Finally, 4-hydroxyindole is prepared by dehydrogenation and isomerization.

 

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