Product Description:
Product Name: 4-hydroxyindole CAS NO:2380-94-1
Synonyms:
4-hydroxy-indole;
1H-Indol-4-ol;
4-hydroxy-1H-indole;
Chemical & Physical Properties:
Appearance: off-white powder
Assay :≥99.0%
Density:1.327g/cm3
Boiling Point:343.2℃ at 760 mmHg
Flash Point: 161.4℃
Melting point: 97-102℃
Used as pharmaceutical intermediates.
Production method: Using resorcinol as raw material, isomerization, catalytic hydrogenation, and then cyclization with ethyl bromopyruvate to prepare 4-oxotetrahydrogumarone carboxylic acid. It is added to a methanol solution saturated with ammonia and heated in an autoclave to generate 4-oxotetrahydroindole. Finally, 4-hydroxyindole is prepared by dehydrogenation and isomerization.
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