4-Amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine CAS NO 151266-23-8

4-Amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine CAS NO 151266-23-8

CAS NO: 151266-23-8

Molecular Formula: C5H4IN5

Molecular Weight: 276.29

EINECS NO: 688-977-5

MDL NO: MFCD03787931

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Product Details

Product Description:

Product Name: 4-Amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine CAS NO: 151266-23-8

 

Synonyms:

3-iodopyrazolo[3,4-d]pyriMidin-4-aMine;

4-Amino-3-iodopyrazolo[3,4-d]pyridine;

 

Chemical & Physical Properties:

Appearance : Off-white to light brown powder.

Assay : ≥99.0%

Density: 2.646g/cm3

Melting point: >300℃

Boiling Point: 498.8℃ at 760 mmHg

Flash Point: 255.5℃

Refractive Index: 1.918

Vapor Pressure: 0.0mmHg at 25°C

PSA: 80.48000

LogP: 1.12090

Pka: 10.5±0.20(Predicted)

Sensitive: Light Sensitive

Λmax: 282nm(lit.)

Solubility: N/A

Category: Building Blocks; Pharmaceutical/API Drug Intermediates; ;Heterocycle-Pyridine series;

 

Safety Information:

HS Code: 2933990090

Signal Word: Warning

Hazard Statements:  H315-H319-H335

Safety Statements: S26; S36/37/39

Risk Statements:R36/37/38

Hazard Codes: Xn

RIDADR: NONH for all modes of transport

 

StorageStored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

 

Application:

3-Iodo-3H-pyrazolo[3,4-d]pyrimidin-4-amine acts as a reagent in the discovery and preparation of CHMFL-FLT3-122 as potent and orally available FLT3 kinase inhibitor for FLT3-ITD positive acute myeloid leukemia. Development and preparation of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes.

Intermediate for Ibrutinib.

 

Our factory manufacture's 3-Iodo-4-Aminopyrazolo[3,4-D]Pyridine, mature technology, stable output, quality assurance.

Inventory Status : In Stock.

 

 

We can provide 3-iodo-4-Amino-1h-Pyrazolo[3,4-D]Pyrimidine COA (certificate of analysis),3-Iodo-1H-Pyrazolo[3,4-D]Pyrimidin-4-ylamine MOA (Method of Analysis), 3-iodo-2H-pyrazolo[3,4-d]pyrimidin-4-amine ROS (Route of synthesis), CAS 151266-23-8 MSDS (Material Safety Data Sheet) and other support for you !

 

 

Ibrutinib And Intermediates

CAS NO

Ibrutinib

936563-96-1

1-Piperidinecarboxylicacid,3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-,1,1-dimethylethylester,(3R)-

1022150-11-3

(S)-1-Boc-3-hydroxypiperidine

143900-44-1

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine

1022150-12-4

5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine

330786-24-8

5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile

330792-70-6

(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-aminedihydrochloride

1701403-10-2

4-Amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine

151266-23-8

4-Phenoxyphenyl boronic acid

51067-38-0

 

 

If you are interested in our products or have any questions, please feel free to contact us!

 

 

Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.


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