4-(3-chloro-4-fiuoro-phenylaMino)-7-fluoro-6-nitroquninazoline CAS 162012-67-1

Product Description

Product Name: 4-(3-chloro-4-fiuoro-phenylaMino)-7-fluoro-6-nitroquninazoline CAS NO:162012-67-1

Synonyms:

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-;

N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine;

N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine;

Chemical & Physical Properties

Appearance :Yellow powder.

Assay : ≥99.0%, EE ≥99.5%

Density: 1.617 g/cm3

Boiling Point:488.589℃ at 760 mmHg

Flash Point:249.29℃

Refractive Index: 1.707

Vapor Pressure: 0mmHg at 25°C

4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline is an intermediate in the synthesis of Afatinib, an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

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