3-Methyl-6-[-3-(trifluoroMethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine CAS 66548-69-4

3-Methyl-6-[-3-(trifluoroMethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine CAS 66548-69-4

CAS NO: 66548-69-4
Molecular Formula: C13H9F3N4
Molecular Weight:278.23
EINECS NO: 636-288-5
MDL NO: MFCD00674912
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Product Details

Product Description:

Product Name: 3-Methyl-6-[-3-(trifluoroMethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine CAS NO:66548-69-4


CL 218,872;

Chemical & Physical Properties:

Appearance : off-white powder

Assay :≥98.0%


Melting point:193-194℃

Solubility: Soluble to 50 mM in DMSO and to 25 mM in ethanol

CL-218,872 is a sedative and hypnotic drug used in scientific research. It has similar effects to sedative-hypnotic benzodiazepine drugs such as triazolam, but is structurally distinct and so is classed as a nonbenzodiazepine hypnotic.

CL-218,872 is a GABAA partial agonist which is selective for the α1 subtype. It has a range of effects including sedative, hypnotic, anxiolytic, anticonvulsant and amnestic actions, however the most prominent actions are sedation and amnesia, and CL-218,872 produces effects very similar to those of the hypnotic imidazopyridine derivative zolpidem in animal studies.



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