(3α,5β,6α)-6-ethyl-3-hydroxy-7-oxo-cholan-24-oic Acid Ethyl Ester CAS 459789-97-0

Product Description:

Product Name: (3α,5β,6α)-6-ethyl-3-hydroxy-7-oxo-cholan-24-oic acid ethyl ester CAS NO:459789-97-0

Synonyms:

ethyl (4R)-4-[(3R,5S,6R,8S,9S,10S,13R,14S,17R)-6-ethyl-3-hydroxy-10,13-dimethyl-7-oxo-1,2,3,4,5,6,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pentanoate;

(4R)-ethyl 4-((3R,5S,6R,7R,10S,13R,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate;

Chemical & Physical Properties:

Appearance : White to off-white powder

Assay : ≥99.0%

Density: 1.046g/cm³

Melting point: N/A

Boiling Point: N/A

Flash Point: N/A

Refractive Index: N/A

PSA: 63.600

LogP: 5.80070

Solubility: Dichloromethane; Chloroform; Ethyl Acetate; DMSO; Methanol;

Category: Standards; Steroids;

Safety Information:

HS Code: 2918990090

Storage:Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Application:1. pharmaceutical intermediate; (3α,5β,6α)-6-ethyl-3-hydroxy-7-oxo-cholan-24-oic acid ethyl ester CAS 459789-97-0 is used the synthesis of primary biliary cirrhosis and non-alcoholic fatty liver disease drug Obeticholic Acid.

2. (3Alpha,5Beta,6Alpha)-6-ethyl-3-hydroxy-7-oxo-cholan-24-oic acid ethyl ester is an intermediate used in the synthesis of 6α-Ethyl Ursodeoxycholic Acid, which is an epimer of Obeticholic Acid. Obeticholic Acid is a derivative of the bile acid Chenodeoxycholic Acid. Obeticholic Acid is a potent activator of the farnesoid X nuclear receptor which reduces liver fat and fibrosis in animal models of fatty liver disease.

Our factory manufacture’s (3α,5β,6α)-6-ethyl-3-hydroxy-7-oxo-cholan-24-oic acid ethyl ester CAS 459789-97-0, mature technology, stable output, quality assurance.

Inventory Status : In Stock.

We can provide CAS 459789-97-0 certificate of analysis( COA), 

Ethyl (R)-4-((3R,5S,6R,8S,9S,10S,13R,14S,17R)-6-ethyl-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate Method of Analysis (MOA), CAS 459789-97-0 Route of synthesis (ROS), Ethyl (3α,5β,6α)-6-ethyl-3-hydroxy-7-oxo-cholan-24-oate Material Safety Data Sheet (MSDS) and other support for you !

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