3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine CAS NO 1022150-12-4

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine CAS NO 1022150-12-4

CAS NO: 1022150-12-4

Molecular Formula: C22H22N6O

Molecular Weight: 386.45

EINECS NO: N/A

MDL NO: MFCD20482137

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Product Details

Product Description:

Product Name: 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine CAS NO:1022150-12-4

 

Synonyms:

3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;

1H-Pyrazolo[3,4-d]pyrimidin-4-amine,3-(4-phenoxyphenyl)-1-[(3R)-3-piperidinyl]-;

 

Chemical & Physical Properties:

Appearance :  White to Pale Yellow powder.

Assay : ≥99.0%

Density: 1.4g/cm3

Melting point:133-136℃

Boiling Point: 626.3℃ at 760 mmHg

Flash Point: 332.6℃

Refractive Index: 1.731

Vapor Pressure: 0.0mmHg at 25°C

PSA: 90.88000

LogP: 4.70230

Pka: 9.00±0.10(Predicted)

Solubility: DMSO (Slightly), Methanol (Slightly).

Category: Piperidines; Chiral Molecules; Pharmaceutical/API Drug Intermediates;

 

Safety Information:

HS Code:  2933399090

 

StorageStored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

 

Application:

1. (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is an intermediate used to prepare pyrazolo-pyrimidine compounds as inhibitors of Bruton's tyrosine kinase. It is also an intermediate for Ibrutinib derivatives.

2. Btk inhibitor 1 R enantiomer is a pyrazolo[3,4-d]pyrimidine derivative as a BTK kinase inhibitor.

3. (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is an intermediate of selective, irreversible Btk inhibitor Ibrutinib (PCI-32765).

 

Our factory manufacture’s (3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine , mature technology, stable output, quality assurance.

Inventory Status : In Stock.

 

We can provide 3-(4-phenoxyphenyl)-1-(3R)-3-piperidinyl-1H-Pyrazolo[3,4-d]pyrimidin-4-amine COA (certificate of analysis), MOA (Method of Analysis), ROS (Route of synthesis), CAS 1022150-12-4 MSDS (Material Safety Data Sheet) and other support for you !

  

 we can supply Ibrutinib And Intermediates:

Ibrutinib And Intermediates

CAS NO

Ibrutinib

936563-96-1

1-Piperidinecarboxylicacid,3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-,1,1-dimethylethylester,(3R)-

1022150-11-3

(S)-1-Boc-3-hydroxypiperidine

143900-44-1

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine

1022150-12-4

5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine

330786-24-8

5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile

330792-70-6

(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-aminedihydrochloride

1701403-10-2

4-Amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine

151266-23-8

4-Phenoxyphenyl boronic acid

51067-38-0


Core Philosophy

People-oriented, innovation;

Quality and Credibility are the life of the company.

  

Our Ideas

Respect and care the nature, the society and human life

Excellent quality, excellent service to meet customer

Grow steadily and continuously, Make employees proud

Hefei Home Sunshine Pharma are willing to spare no effort for human health.

 

 

FAQ:


Q1: How to confirm the Product Quality before placing orders?

A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

 

Q2: How about delivery leadtime?

A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

 

Q3:Is there a discount?

A:Different quantity has different discount.

 

Q4: How do you treat quality complaint?

A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.


Q5. How about the packing?

Usually we provide the packing as 25 kg / bag or carton. Of course, if you have special requirements on them, we will according to you.


If you are interested in our products or have any questions, please feel free to contact us!

 

 

Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.


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