Product Name: 2-hydroxy-3-methoxy-3,3-diphenylpropanoic acid CAS 178306-51-9
Chemical & Physical Properties:
Appearance :white solid
Boiling Point: 430.3℃ at 760 mmHg
3-methoxy-2-hydroxy-3,3-diphenylpropionic acid is used to Ambrisentan intermediate.
Anrisentan is a selective endothelin receptor antagonist, which has the effects of reducing endogenous vasoconstriction, antiproliferative and anti-inflammatory. Anrisentan is a specific endothelin receptor A (ETA receptor) inhibitor developed by Gilead Science Company. It is a highly selective ETA receptor antagonist that can block the binding of ET and ETA, thereby blocking ETA-mediated pulmonary vasoconstriction and smooth muscle cell proliferation.
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