2-hydroxy-3-methoxy-3,3-diphenylpropanoic Acid CAS 178306-51-9

2-hydroxy-3-methoxy-3,3-diphenylpropanoic Acid CAS 178306-51-9

CAS NO: 178306-51-9
Molecular Formula: C16H16O4
Molecular Weight: 272.296
EINECS NO: 605-820-8
MDL NO: MFCD13152279
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Product Details

Product Description:

Product Name: 2-hydroxy-3-methoxy-3,3-diphenylpropanoic acid CAS 178306-51-9





rac-2-hydroxy-3-methoxy-3,3-diphenylpropionic acid;



Chemical & Physical Properties:

Appearance :white solid

Assay :≥99.0%

Density:1.25 g/cm3

Boiling Point: 430.3℃ at 760 mmHg

Flash Point:158.4℃


3-methoxy-2-hydroxy-3,3-diphenylpropionic acid is used to Ambrisentan intermediate.

Anrisentan is a selective endothelin receptor antagonist, which has the effects of reducing endogenous vasoconstriction, antiproliferative and anti-inflammatory. Anrisentan is a specific endothelin receptor A (ETA receptor) inhibitor developed by Gilead Science Company. It is a highly selective ETA receptor antagonist that can block the binding of ET and ETA, thereby blocking ETA-mediated pulmonary vasoconstriction and smooth muscle cell proliferation.



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