2-Chlorobromobenzene CAS 694-80-4

2-Chlorobromobenzene CAS 694-80-4

CAS NO: 694-80-4
Molecular Formula: C6H4BrCl
Molecular Weight: 191.453
EINECS NO: 211-775-1
MDL NO: MFCD00000532
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Product Details

Product Description:

Product Name: 2-Chlorobromobenzene CAS  NO:694-80-4



2-bromobenzyl alcohol;


o-Bromobenzyl alcohol;



Chemical & Physical Properties:

Appearance : clear colorless to yellow-orange liquid

Assay :≥99.0%

Density:1.649 g/cm3

Boiling Point:204℃ at 760 mmHg

Flash Point:70℃

Melting Point:-2℃


1-Bromo-2-chlorobenzene is a reagent in the preparation of arylpiperidines and aryltetrahydropyridines as 5-HT2C agonists..

Ortho-bromochlorobenzene is 2-bromochlorobenzene, it also has two isomers, namely m-bromochlorobenzene and p-bromochlorobenzene. The three compounds are all toxic and much stronger than the corresponding dichloride. It reacts with metal Mg in ether to produce p-chlorophenyl magnesium bromide. Take o-chloroaniline as raw material, mix with concentrated hydrobromic acid, reduce the temperature to 0℃, and quickly add sodium nitrite aqueous solution under stirring to nitridize o-chloroaniline to form diazonium salt, which should be controlled during the reaction The temperature does not exceed 10°C. Then use the Sandmeyer reaction, add the catalyst cuprous bromide and hydrobromic acid to the reaction system to decompose the diazonium salt. The decomposition reaction is carried out at the boiling temperature. After the reaction is completed, stand still, take out the lower organic layer and wash it with water. Drying to remove water, vacuum distillation, can be obtained o-bromochlorobenzene.


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