2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol CAS 142569-70-8

2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol CAS 142569-70-8

CAS NO: 142569-70-8
Molecular Formula: C29H28ClNO2
Molecular Weight: 457.991
EINECS NO: 604-295-2
MDL NO: MFCD09038584
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Product Details

Product Description:

Product Name: 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol CAS NO:142569-70-8

 

Synonyms:

(S)-1-(3-(2-(7-Chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propan-1-ol;

2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol;

 

Chemical & Physical Properties:

Appearance : White to light yellow powder

Assay :≥98.0%

Density: 1.244g/cm3

Boiling Point:636.8℃at 760 mmHg

Flash Point:338.9℃

 

Montelukast Intermediate.

Montelukast can effectively inhibit the physiological effects of the binding of LTC4, LTD4 and LTE4 to the CysLT1 receptor without any receptor agonistic activity. There is a second type of cysteyl leukotriene receptor (CysLT2) in the lungs, but it may be limited to the blood vessels. So far, these two receptors have not been cloned, so the situation of CysLT receptor is mainly explained by receptor binding test and pharmacological analysis. It is now believed that montelukast sodium does not antagonize the CysLT2 receptor.

 

 

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