1-Piperidinecarboxylicacid,3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-,1,1-dimethylethylester,(3R)- CAS NO 1022150-11-3

1-Piperidinecarboxylicacid,3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-,1,1-dimethylethylester,(3R)- CAS NO 1022150-11-3

CAS NO: 1022150-11-3

Molecular Formula: C27H30N6O3

Molecular Weight: 486.57

EINECS NO:N/A

MDL NO: MFCD28167899

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Product Details

Product Description:

Product Name: 1-Piperidinecarboxylicacid,3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-,1,1-dimethylethylester,(3R)- CAS 1022150-11-3

 

Synonyms:

N-Boc-Ibrutinib;

(R)-3-[4-Amino-3-(4-phenoxy-phenyl)-pyrazolo[3,4-d]pyrimidin-1-yl]-piperidine-1-carboxylicacidtert-butylester;

3-[4-Amino-3-(4-phenoxy-phenyl)-pyrazolo[3,4-d]pyrimidin-1-yl]-piperidine-1-carboxylic acid tert-butyl ester;

 

Chemical & Physical Properties:

Appearance :  White to off-white powder.

Assay : ≥99.0%

Density: 1.31g/cm3

Melting point: 103-106℃

Boiling Point: 673.9℃ at 760 mmHg

Flash Point: 361.4℃

Refractive Index: 1.662

Vapor Pressure: 0.0mmHg at 25°C

PSA: 108.39000

LogP: 5.95890

Pka: 4.09±0.30(Predicted)

Solubility: DMSO (Slightly), Ethyl Acetate (Slightly)

Category: Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Intermediates;

 

Safety Information:

HS Code:  2933599090

 

StorageStored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

 

Application:

(R)-tert-Butyl3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate is an impurity of Ibrutinib, which is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.

 

 

Our factory manufacture’s (R)-tert-Butyl3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate, mature technology, stable output, quality assurance.

Inventory Status : In Stock.

 

 

We can provide tert-butyl (R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate COA (certificate of analysis), tert-butyl (3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3.4-d]pyrimidin-1-yl]piperidine-1-carboxylate MOA (Method of Analysis),  ROS (Route of synthesis),CAS 1022150-11-3 MSDS (Material Safety Data Sheet) and other support for you !


 we can supply Ibrutinib And Intermediates:


Ibrutinib And Intermediates

CAS NO

Ibrutinib

936563-96-1

1-Piperidinecarboxylicacid,3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-,1,1-dimethylethylester,(3R)-

1022150-11-3

(S)-1-Boc-3-hydroxypiperidine

143900-44-1

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine

1022150-12-4

5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine

330786-24-8

5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile

330792-70-6

(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-aminedihydrochloride

1701403-10-2

4-Amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine

151266-23-8

4-Phenoxyphenyl boronic acid

51067-38-0

   

If you are interested in our products or have any questions, please feel free to contact us!

 

 

Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.


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